Karnasa500 ( mesalazine )


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white capsules containing mesalazine in  dose of 500 mg



inflammatory bowel disease


How to use 

The dose of this medicine will be different for different patients, and always the doctor tells how to use the
medicine, but the usual dose is:

For inflammatory bowel disease: long-acting oral dosage form (extended-release capsule)
Adults: 1 gram four times a day for up to eight weeks.
Children: Use and dose must be determined by your doctor.

Missed dose: take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose
and go back to your regular dosing schedule. Do not double doses.


Side effects
Every medicine by the side of therapeutic effects may cause some adverse effects, although not everybody gets them.
Stop taking this medicine and go to a doctor if any of the following effects occur:

  • Less common: abdominal or stomach cramps or pain (severe), bloody diarrhea, fever, headache (severe), skin rash and itching ,anxiety, back or stomach pain (severe), pale skin, chest pain; possibly moving to the left arm or neck or shoulders, fast heartbeat, nausea or vomiting, shortness of breath, swelling of stomach, unusual tiredness, yellow eyes or skin,acne, back or joint pain, flatulence, indigestion, loss of appetite, loss of hair
  • More common: abdominal or stomach cramps or pain (mild), diarrhea (mild), dizziness, headache (mild), runny or stuffy nose or sneezing.



  • Before taking this medicine tell your doctor if you are taking any other medicines as prescribed and non-prescribed medicines.
  • Mesalazine is available only with your doctor's prescription.
  • Tell your doctor if you have ever had any unusual or allergic reaction to Mesalazine or any other medicines, foods, dyes, and preservatives.
  •  Keep taking this medicine for the full time of treatment, even if you begin to feel better after a few days, Do not miss any doses.
  •  Take this medicine with or right after a meal with a full glass of water, unless otherwise directed by your doctor.
  • Swallow the capsule whole. Do not break, crush, or chew it before swallowing.
  • Do not take medicines used to treat indigestion within 2 hours before or after taking this medicine.
  • Your progress should be checked at regular visits by the doctor.
  •  You may sometimes notice what looks like small beads in your stool. These are just the empty shells that are left after the medicine has been absorbed into your body.
  •  It is important to monitor renal function, CBC (particularly in elderly patients), hepatic function prior to and periodically during therapy.
  • Before using KARNASA tell your doctor if you have any medical problems, especially  allergy to sulfasalazine, kidney disease, narrowing of the tube where food passes out of the stomach, hepatic disease, phenylketonuria
  •  Use with caution in kidney impairment, elderly patients and pulmonary diseases.


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